KMID : 0604519890150010051
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Journal of the Society of Cosmetic Scientists of Korea 1989 Volume.15 No. 1 p.51 ~ p.62
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A Study on the Inclusion Complexation of Octyldimethyl p-aminobengoate with \brta -Cyclodextrin
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Lee Chang-Hak
So Boo-Young Kim Young-Soo
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Abstract
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Inclusion complex formation of octyldimethl p-aminobenzoate with beta-cyclodextrin in aqueous solution and in the solid state was studied by the solubility method, spectroscopic(UV, FT-lR) and X -ray diffractometry. The solid complex of octyldimethy p-aminobenzoate with beta-cyclodextrin was obtained in molar ratio of 1 : 2(guest/host). A spatial relationship between host and guest molecule was clearly reflected in the magnitude of the apparent stability constant (K¡¯) and in the stoichiometry of the inclusion complex. Furthermore, a typical type Bs phase-solubility diagram was obtained for octyldimethyl p-aminobenzoate and p -cyclodextrin in water at 25^{circ}C. The results indicated that the solubility of the guest molecule was higher by the formation of beta-cyclodextrin inclusion complex
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